Treatment Suggestions for PersonalHealthInformation@Restricted.EU

This report is for PersonalHealthInformation@Restricted.EU using this sample BiomeSight:2025-03-04 Self πŸ›‘ 🀧 . It uses their reported medical conditions, microbiome sample, US National Library of Medicine, and a fuzzy logic expert system to compute recommendations balancing study reliability and contraindications. These suggestions should always be reviewed by a medical professional before starting.

NOTA BENE: This is working solely from published studies. Other suggestions algorithms are available on Microbiome Prescription. The URL above may be sent to your MD if you wish to share it.

The reported condition(s) are

This person has a significant amount of bacteria known to form biofilms

Substances with a 🦠 are reported to reduce biofilms. See for studies.

  1. Depression - Depressive Disorder
    1. Omega-3 Fatty Acids: Some studies suggest that omega-3 supplements, particularly those rich in EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), might have modest benefits as adjuncts to traditional treatments for depression. Omega-3s are essential for brain health, and they may have some mood-stabilizing properties.

    2. Vitamin D: Low levels of vitamin D have been associated with depression. While the exact relationship is complex and not fully understood, maintaining adequate vitamin D levels through supplements or exposure to sunlight may support overall mental health.

    3. B Vitamins: Some B vitamins, such as B6, B9 (folate), and B12, are involved in neurotransmitter synthesis and may have a role in mood regulation. Folate deficiency, in particular, has been linked to depressive symptoms.

    4. Probiotics: The gut-brain connection has led to studies exploring the potential impact of probiotics on mental health. Research suggests that gut health may influence mood, and some studies propose that certain probiotics might have a modest effect on reducing depressive symptoms. However, more research is needed to determine specific strains, dosages, and their impact on depression.

Significant Bacteria Shifts

Based on the existing literature on the US National Library of Medicine and this microbiome sample, we have the following matches for bacteria shifts. There is a growing body of literature finding that the effectiveness of interventions depends on the existing microbiome. We filter by documented interventions that helps some with this condition and suggestions based on this person's specific microbiome to produce this "double validated" list.


Acidaminococcus - genus : High 15
Actinomycetes - class : Low 2
Actinomycetota - phylum : Low 2 15 29
Bacillota - phylum : Low 2 15 16 28 30
Bacteroidaceae - family : High 2 7
Bacteroidales - order : High 1
Bacteroides - genus : High 4 6 11 13 20 22 23
Bacteroides fragilis - species : High 12
Bacteroidota - phylum : High 30
Clostridia - class : Low 15
Collinsella - genus : Low 11
 
Coprococcus - genus : Low 3 7 14 15 17 21 25
Eubacteriales - order : Low 15 26
Lachnospiraceae - family : Low 2 6 8 11
Oscillospiraceae - family : Low 7 11 22
Parabacteroides distasonis - species : High 10
Pseudomonadota - phylum : Low 15
Ruminococcaceae - family : Low 2 5 19 26 27 28
Ruminococcus - genus : Low 13 15 24
Streptococcus - genus : Low 9
Sutterella - genus : Low 7 18
Sutterellaceae - family : Low 7

Cross Validated Suggestions

The following improves the bacteria identified above and also is reported in the literature of helping some people with this condition. Each is link to the source study.


5,6-dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium {Berberine} 73
(2->1)-beta-D-fructofuranan {Inulin} 48
3,3',4',5,7-pentahydroxyflavone {Quercetin} 47
3,5,7-trihydroxy flavanone-7-rhamnoglucoside {Hesperidin} 37
a-Amino-3-indolepropionic acid {Tryptophan} 81
Agaricus bisporus {White button mushrooms} 37
Akkermansia muciniphila {Pendulum Probiotic} 50 71 75 83 90 101 121
alpha-linolenic acid {Omega-3} 40 41 47 57
arabinogalactan {arabinogalactan} 95
Bifidobacterium animalis {B. animalis} 114
Bifidobacterium breve {B. breve} 51 54 98 104
bifidobacterium infantis {B. infantis} 87
bifidobacterium pseudocatenulatum {B. pseudocatenulatum } 109
Biotin {Vitamin B7} 85
blueberry 47
Caffeine 47
Camellia sinensis {oolong tea} 57
carvedilol,(prescription) 112
cefaclor hydrate (antibiotic) 70
Citrus limon {Lemon} 55
Coffee 47
coptis chinensis {Chinese goldthread } 58
Crocus sativus {Saffron} 52 57
Cuminum cyminum {Cumin} 57
dietary fiber 47
Diferuloylmethane {Curcumin} 117
eicosapentaenoic acid (EPA),docosahexaenoic acid (DHA) {Fish Oil} 47 57
Epicatechin {Green tea polyphenol} 47
ethinylestradiol,(prescription) 111
Faecalibacterium prausnitzii {Faecalibacterium prausnitzii} 110
Finnish Probiotic {Valio Probiotic} 88 107
fluoxetine hydrochloride,(prescription) 92
folate {Vitamin B9} 39 40
fruit 38 46
Gallus domesticus {Chicken} 46
Ganoderma sichuanense {Reishi Mushroom} 106
Glycine max x Aspergillus oryzae {Miso} 47
green tea 47
Hericium erinaceus {Lion's Mane Mushroom } 77
Heyndrickxia coagulans {B. coagulans} 31 32 115
Ipomoea batata {Purple sweet potatoes} 37
kefir 99
Kimchi 37
Lacticaseibacillus casei {L. casei} 86 104
Lacticaseibacillus rhamnosus {l. rhamnosus}🦠 63 72 93 96 102 117
 
lactobacillus helveticus {L. helveticus} 51 58 76 91
lactobacillus helveticus,lactobacillus rhamnosus 89 93
Lactobacillus plantarum {L. plantarum} 47 49 51 56 58 62 64 104 108 113
lactobacillus rhamnosus gg,bifidobacterium animalis lactis ,lactobacillus paracasei {cvs maximum strength probiotic} 84
Lactococcus lactis {Streptococcus lactis}🦠 52
Lentinula edodes {Shiitake Mushroom} 37
Levilactobacillus brevis {L.brevis} 49
Limosilactobacillus fermentum {L. fermentum} 97
long-term, moderate-intensity exercise {exercise} 74 80 103 116 119 120
low carbohydrate diet 47
Lycium barbarum x Lycium chinense, {Goji Fruit, Juice} 57
Malus domestica {apple} 79
mirtazapine,(prescription) 45
Mixture of Vitamin B? {B Vitamins} 33
Musa acuminata {Banana} 37
nuts 46 47
oligosaccharides {oligosaccharides} 89
Orange Juice 55
Phaseolus vulgaris {Boston bean} 46
Pisces {Fish} 38 47
polyphenols 47
propofol,(prescription) 118
Pulses, Beans 46
Pyridoxine {Vitamin B6} 38
Pyroguaiac acid {Guaiacol} 79
resveratrol-pterostilbene {grapes, blueberries} 47
resveratrol-pterostilbene x Quercetin {quercetin x resveratrol} 47
Rhodiola rosea {Rosavin} 57
Rubus {Raspberries} 47 61
Selenomethionine {Selenium supplement} 94
Solanum tuberosum {Potatoes} 82
soy 46 47
ß-glucan {Beta-Glucan} 66 67 68 69
Streptococcus faecalis, Clostridium butyricum, Bacillus mesentericus {Bio-three} 115
Streptococcus salivarius subsp. thermophilus {S. thermophilus} 105
tea 100
Traditional Mediterranean diet {Mediterranean diet} 46
Vaccinium {Cranberry} 47
vegetable 38 46
vegetarians 46
venlafaxine,(prescription) 42
vitamin d🦠 33 34 35 36 47 78
Whole Cow milk {Whole Milk} 37
whole-grain diet 46
yogurt 47

Probiotic Species Impact by R2 associations

See Background

  1. Roseburia intestinalis - rank: 466
  2. Anaerobutyricum hallii - rank: 453
  3. Christensenella minuta - rank: 431
  4. Faecalibacterium prausnitzii - rank: 424
  5. Blautia wexlerae - rank: 423
  6. Blautia hansenii - rank: 351
  7. Enterococcus faecium - rank: 351
  8. Lactococcus cremoris - rank: 261
  9. Akkermansia muciniphila - rank: 196
  10. Bifidobacterium catenulatum - rank: 176
  11. Bifidobacterium adolescentis - rank: 160
  12. Lactococcus lactis - rank: 148
  13. Bifidobacterium longum - rank: 142
  14. Bifidobacterium longum subsp. infantis - rank: 139
  15. Bifidobacterium breve - rank: 136
  16. Leuconostoc mesenteroides - rank: 123
  17. Levilactobacillus brevis - rank: 118
  18. Bifidobacterium bifidum - rank: 106
  19. Streptococcus thermophilus - rank: 98
  20. Ligilactobacillus salivarius - rank: 90
  21. Bifidobacterium pseudocatenulatum - rank: 87
  22. Segatella copri - rank: 74
  23. Escherichia coli - rank: 54
  24. Lacticaseibacillus paracasei - rank: 40
  25. Enterococcus faecalis - rank: 36
  26. Lactiplantibacillus plantarum - rank: 35
  27. Latilactobacillus sakei - rank: 26
  28. Lacticaseibacillus rhamnosus - rank: 26
  29. Phocaeicola coprocola - rank: 13

Alternative Names

Depending on where you are located, some names may be unfamiliar. Some of the items listed may not be identical but are deemed to be reasonable approximations.

5,6-dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium {Berberine}Found in goldenseal, Chinese goldthread, barberry, tree turmeric, Oregon grape
(2->1)-beta-D-fructofuranan {Inulin}Fructan, Polyfructose, Alpha-D-glucopyranosyl-beta-D-fructofuranosyl-D-fructofuranoside, usually from Chicory root, Jerusalem artichoke
3,3',4',5,7-pentahydroxyflavone {Quercetin}quercetin aglycone,bioflavonoid,a type of flavonol
3,5,7-trihydroxy flavanone-7-rhamnoglucoside {Hesperidin}Cirantin, Ciratin,Hesperidina
a-Amino-3-indolepropionic acid {Tryptophan}Found in Chicken and Turkey, sardines and Lobsters
Agaricus bisporus {White button mushrooms}Common mushroom,White mushroom,Button mushroom,Cultivated mushroom,Table mushroom,Champignon,Champignon de Paris
alpha-linolenic acid {Omega-3}ALA. Plant based, Flaxseed, otherwise see Fish oil NOT a-Lipoic acid (also ALA)
arabinogalactan {arabinogalactan}Galactoarabinan,Galactoarabinin,AG,Ara-6,source Larch Trees and Leeks
Bifidobacterium animalis {B. animalis}Bifidobacterium longum subsp. animalis biotype a,Bifidobacterium animalis subsp. lactis
Biotin {Vitamin B7}Vitamin H
Camellia sinensis {oolong tea}Blue Tea,Qingcha,Wulong
carvedilol,(prescription) (acarden, anisto, antibloc, apo-carve, apo-carvedilol, arlec, artist, aspen carvedilol, atenote, atram, avedol, avernol, betacar, betacard, betaplex, bicol, bidecar, blocar, bloquedil, blorec, cadil,...
cefaclor hydrate (antibiotic) (acef, aczebri, ag-clor, alenfral, alfacet, alfatil, ambiclor, ambit, an bu, articlor, beinuoke, bi li, camirox, ccl, ceclodan, ceclomek, ceclor, ceclor mr, ceclor retard, ceclordox, cefabac, cefachl...
Citrus limon {Lemon}Citron,LimΓ³n,Zitrone,LimΓ£o
coptis chinensis {Chinese goldthread }Coptide chinois,Golden thread,Yellowroot,Cankerroot,Mouth root,Huang Lian
Crocus sativus {Saffron}Zafran,Kesar,AzafrΓ‘n,Safran,Zafferano
Cuminum cyminum {Cumin}Jeera,Cumino,KΓΌmmel,Comino,Kumin,Kamun,Jira,Jintan
Diferuloylmethane {Curcumin}Extract from Turmeric (which contains other chemicals)
eicosapentaenoic acid (EPA),docosahexaenoic acid (DHA) {Fish Oil}Typically from salmon, mackerel, and sardines
Epicatechin {Green tea polyphenol}Epigallocatechin-3-gallate (EGCG),(-)-Epicatechin, Found in Camellia sinensis (tea plant),Cecropia hololeuca,Apples,Cocoa
ethinylestradiol,(prescription) (abelonelle 28, acelyn, acotol, adele, adelle, adepal, adexa, adoless, afrodita, aida, aidee, aidulan, ailyn, akraz, alcmena, aleli, alenini, alenvona, alesse, alesse 21, alesse 28, alesse-21, alesse...
Faecalibacterium prausnitzii {Faecalibacterium prausnitzii}Next Generation Probiotic
Finnish Probiotic {Valio Probiotic}lactobacillus rhamnosus gg,lactobacillus,rhamnosus,propionibacterium freudenreichii,bifidobacterium breve
fluoxetine hydrochloride,(prescription) (actan, afeksin, andepin, anisimol, anxetin, apo-fluoxetine, barozac, bioxetin, daforin, deprelafax, deprenon, deprexetin, deprimaks, dinalexin, felixina, fledore, fledore-a, floatin, florak, floxet,...
folate {Vitamin B9}folic acid when referring to its synthetic form, folacin, pteroyl-L-glutamic acid, Wills factor
fruitFruits(Raw)
Gallus domesticus {Chicken}Descendent of Tyrannosaurus rex (58% of the same DNA)
Ganoderma sichuanense {Reishi Mushroom}Lingzhi,Mushroom of Immortality,Varnish shelf,Artists conk,Ganoderma lucidum
Glycine max x Aspergillus oryzae {Miso}Japanese fermented soybean paste made with Aspergillus oryzae
Hericium erinaceus {Lion's Mane Mushroom }Yamabushitake (Japanese), Bearded Tooth Fungus, Monkey's Head Mushroom, Hedgehog Mushroom, Old Man's Beard,Bearded Hedgehog
Heyndrickxia coagulans {B. coagulans}Was Bacillus coagulans,AKA Weizmannia faecalis,lactobacillus sporogenes
Ipomoea batata {Purple sweet potatoes}Okinawan sweet potato, Murasaki sweet potato: Often confused with purple yams [different]
Lacticaseibacillus casei {L. casei}Streptobacterium casei,Lactobacillus casei
Lacticaseibacillus rhamnosus {l. rhamnosus}lactobacillus rhamnosus, Lactobacillus casei subsp. rhamnosus
lactobacillus acidophilus {L. acidophilus}Bacillus acidophilus
lactobacillus helveticus,lactobacillus rhamnosus l helveticus,l rhamnosus (probiotics)
Lactobacillus plantarum {L. plantarum}lactobacillus plantarum, Lactobacillus arabinosus
Lentinula edodes {Shiitake Mushroom}Black mushroom, Chinese black mushroom, Sawtooth oak mushroom, Golden oak mushroom, Oakwood mushroom
Levilactobacillus brevis {L.brevis}old name Lactobacillus brevis
Limosilactobacillus fermentum {L. fermentum}Lactobacillus fermentum
long-term, moderate-intensity exercise {exercise}Shifts not seen with short-term, high-intensity exercise
low carbohydrate dietlow-sugar
Lycium barbarum x Lycium chinense, {Goji Fruit, Juice}Wolfberry,Chinese wolfberry, Matrimony vinem, Himalayan goji, Tibetan goji, Ningxia wolfberry, Chinese boxthorn, Fruktus lycii,Gougizi
Malus domestica {apple}Apple skin
mirtazapine,(prescription) (adco-mirteron, afloyan, amirel, apo-mirtazapine, arintapin smelt, aspen mirtazapine, auro-mirtazapine od, avanza, azapin, bilanz, calixta, chemmart mirtazapine, ciblex, combar, comenter, depreram, d...
Mixture of Vitamin B? {B Vitamins}Vitamin B1,thiamine hydrochloride,Vitamin B-12,vitamin b2,Riboflavin,vitamin B3,niacin,Vitamin B5,Vitamin B6,pyridoxine hydrochloride,vitamin B7, biotin,Vitamin B9,folic acid
Musa acuminata {Banana}Musa Γ— paradisiaca, plantains,Cavendish banana, Green banana resistant starch
oligosaccharides {oligosaccharides}includes Fructo-oligosaccharides (FOS),Galacto-oligosaccharides (GOS),Mannan oligosaccharides (MOS),Human milk oligosaccharides (HMOs)
Orange JuiceCitrus
Phaseolus vulgaris {Boston bean}Navy bean,Haricot bean,Pearl haricot bean,Boston bean,White pea bean,White Kidney Bean,Pinto Bean
Pisces {Fish}includes Agnatha,Chondrichthyes ,Osteichthyes
propofol,(prescription) (1% propofol maruishi, 2% propofol maruishi, anefol, anepol, anesia, anespro, anesvan, anvar, aquafol, b braun propofol, b.braun propofol-lipuro 0.5 %, blofop, critifol, di shi ning, diprifol, dipriv...
Pulses, BeansBlack Beans,Broad Beans,dry beans, dry broad beans, dry peas, chickpeas, cow peas, pigeon peas, lentils, Bambara beans, vetches, lupins
Pyridoxine {Vitamin B6}Pyridoxine,Pyridoxal,Pyridoxamine
Pyroguaiac acid {Guaiacol}polyphenol, includes Eugenic acid. found in Coffee, smoked foods, Scotch Whiskey
resveratrol-pterostilbene {grapes, blueberries}grape seed/polyphenols/red wine
resveratrol-pterostilbene x Quercetin {quercetin x resveratrol}Mixture of the two
Rhodiola rosea {Rosavin}Rhodiola,Golden root,Rose root,Arctic root,Hong Jing Tian (Chinese),Rosenroot
Rubus {Raspberries}Rubus occidentalis (black raspberry),Rubus leucodermis (whitebark raspberry),Rubus parvifolius (Australian native raspberry),Rubus phoenicolasius (wine raspberry or wineberry),Rubus strigosus (America...
Selenomethionine {Selenium supplement}Sodium selenate, Methylselenocysteine, Selenocysteine. Found in Brazil Nuts, Tuna, Halibut and Sardines
Solanum tuberosum {Potatoes}Spud,Tater,Earth apple
soySoymilk
ß-glucan {Beta-Glucan}Beta-D-glucose polysaccharide, found in Oats, Barley, Rye, Wheat, oyster mushroom, sea weed
Streptococcus faecalis, Clostridium butyricum, Bacillus mesentericus {Bio-three}A blend of Streptococcus faecalis, Clostridium butyricum, Bacillus mesentericus
Streptococcus salivarius subsp. thermophilus {S. thermophilus}Streptococcus thermophilus
Traditional Mediterranean diet {Mediterranean diet}Mediterranean-style diet,Mediterranean eating pattern,Mediterranean dietary pattern
Vaccinium {Cranberry}May include Lingonberry
vegetarianslacto-ovo-vegetarian diet
venlafaxine,(prescription) (alfaxin, alventa, amfax, anapresin, anapresin sr, argofan, axyven, conervin retard, defaxine, depretaxer, deprexor, deprixol, ectien xr, efaxine xr, efectin er, efexor, efexor xr, effegad er, effexi...
vitamin dcholecalciferol,Vitamin D3, activated 7-dehydrocholesterol
whole-grain dietwhole grain,bran

Suggestions Impact On Each Bacteria Picked

Reviewing substances reported to help with this condition on the US National Library of Medicine, and which will correct the above bacteria shifts. the following are recommended. Some bacteria may lack literature because none of the studied substances for the condition(s) are known to modify the bacteria.

Additional Suggestions

There are many other interventions computed to correct the bacteria shifts/abnormalities seen with this person. This is based on not-published studies and patent pending methods for selecting the bacteria. The suggestions are based on studies from the US National Library of Medicine modifying those bacteria. The top 30 suggestions are listed below and the top 30 items to avoid.

Items to add

Items to avoid

  1. Probiotic Mixture 2 {Vetafarm Probotic}
  2. Shen Ling Bai Zhu San {?????}
  3. Cichorium intybus {Chicory}
  4. Rheum Γ— hybridum {Rhubarb}
  5. walnuts
  6. Bovine Milk Products {Dairy}
  7. Lactobacillus gasseri {L.gasseri}
  8. Taraxacum officinale {Dandelion}
  9. 2-hydroxyethyl)trimethylazanium {choline}
  10. Arctium lappa {Burdock Root}
  11. Nicotine, Nicotine Patch
  12. high-fat diets
  13. Secale cereale {Rye}
  14. terpenophenolics {cannabinoids}
  15. Lentilactobacillus kefiri {Kefibios}
  16. Probiotic Mixture 1 {Japanese Vet Probiotic}
  17. Dodecanoic acid {Lauric acid}
  18. Camel Milk
  19. Euterpe oleracea {Acai}
  20. bifidobacterium lactis,streptococcus thermophilus probiotic
  21. Arthrospira platensis {Spirulina}
  22. Decoction of Four Noble Drugs {Sijunzi Decoction (SJZD)}
  23. Tudca
  24. (2E,4E)-5-(1,3-Benzodioxol-5-yl)-1-(1-piperidinyl)-2,4-pentadien-1-one {Piperine}
  25. Momordica charantia {Bitter gourd}
  26. Echinacea Moench {Echinacea}
  27. Rhubarb x Peony {Rhubarb Peony Decoction}
  28. Carum carvi {Caraway}
  29. Menta Γ— piperita {peppermint}
  30. Lactobacillus mucosae
  1. Slow digestible carbohydrates. {Low Glycemic}
  2. Fiber, total dietary
  3. fruit/legume fibre
  4. High-fibre diet {Whole food diet}
  5. Abstention from eating {Fasting}
  6. wheat
  7. Outer Layers of Triticum aestivum {Wheat Bran}
  8. fucoidan {Brown Algae Extract}
  9. pectin {pectin}
  10. Human milk oligosaccharides (prebiotic, Holigos, Stachyose)
  11. grapes
  12. laminaria digitata {Oarweed}
  13. Hydrastis canadensis {Goldenseal}
  14. Grape Polyphenols {Grape Flavonoids}
  15. resistant starch
  16. Poly[ß-D-xylopyranose(1->4)] {Xylan}
  17. Amylum {Starch}
  18. ketogenic diet
  19. henopodium quinoa {Quinoa}
  20. oolong teas
  21. Saccharomyces cerevisiae var boulardii {S. boulardii}
  22. Polydextrose {polydextrose}
  23. ß-lactoglobulin {Whey}
  24. Hordeum vulgare {Barley}
  25. alpha-tocopherol {Vitamin E}
  26. Ginkgo biloba {Ginkgo}??
  27. pseudo-cereals {amaranth,quinoa, taro,buckwheat}
  28. Ferrum {Iron Supplements}
  29. 2H-1?6,2-benzothiazol-1,1,3-trione {Saccharin}
  30. 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one {Apigenin }

Reference

The following is a partial list of the critical citations used above. Click on πŸ“š to go to study

1 πŸ“šβ€ƒ
The role of microbiota in the pathogenesis of schizophrenia and major depressive disorder and the possibility of targeting microbiota as a treatment option
Oncotarget (Oncotarget ) Vol: 8 Issue: 59 Pages: 100899-100907 Pub: 2017 Sep 27 ePub: 2017 Sep 27 Authors Lv F,Chen S,Wang L,Jiang R,Tian H,Li J,Yao Y,Zhuo C
2 πŸ“šβ€ƒ
Altered fecal microbiota composition in patients with major depressive disorder.
Brain, behavior, and immunity (Brain Behav Immun ) Vol: 48 Issue: Pages: 186-94 Pub: 2015 Aug ePub: 2015 Apr 13 Authors Jiang H,Ling Z,Zhang Y,Mao H,Ma Z,Yin Y,Wang W,Tang W,Tan Z,Shi J,Li L,Ruan B
3 πŸ“šβ€ƒ
The neuroactive potential of the human gut microbiota in quality of life and depression.
Nature microbiology (Nat Microbiol ) Vol: 4 Issue: 4 Pages: 623-632 Pub: 2019 Apr ePub: 2019 Feb 4 Authors Valles-Colomer M,Falony G,Darzi Y,Tigchelaar EF,Wang J,Tito RY,Schiweck C,Kurilshikov A,Joossens M,Wijmenga C,Claes S,Van Oudenhove L,Zhernakova A,Vieira-Silva S,Raes J
4 πŸ“šβ€ƒ
Similar Fecal Microbiota Signatures in Patients With Diarrhea-Predominant Irritable Bowel Syndrome and Patients With Depression.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association (Clin Gastroenterol Hepatol ) Vol: 14 Issue: 11 Pages: 1602-1611.e5 Pub: 2016 Nov ePub: 2016 Jun 4 Authors Liu Y,Zhang L,Wang X,Wang Z,Zhang J,Jiang R,Wang X,Wang K,Liu Z,Xia Z,Xu Z,Nie Y,Lv X,Wu X,Zhu H,Duan L
5 πŸ“šβ€ƒ
Reductions in anti-inflammatory gut bacteria are associated with depression in a sample of young adults.
Brain, behavior, and immunity (Brain Behav Immun ) Vol: Issue: Pages: Pub: 2020 Mar 27 ePub: 2020 Mar 27 Authors Liu RT,Rowan-Nash AD,Sheehan AE,Walsh RFL,Sanzari CM,Korry BJ,Belenky P
6 πŸ“šβ€ƒ
Feeling down? A systematic review of the gut microbiota in anxiety/depression and irritable bowel syndrome.
Journal of affective disorders (J Affect Disord ) Vol: 266 Issue: Pages: 429-446 Pub: 2020 Apr 1 ePub: 2020 Jan 22 Authors Simpson CA,Mu A,Haslam N,Schwartz OS,Simmons JG
7 πŸ“šβ€ƒ
Altered Composition of Gut Microbiota in Depression: A Systematic Review.
Frontiers in psychiatry (Front Psychiatry ) Vol: 11 Issue: Pages: 541 Pub: 2020 ePub: 2020 Jun 10 Authors Barandouzi ZA,Starkweather AR,Henderson WA,Gyamfi A,Cong XS
8 πŸ“šβ€ƒ
Flavonoid-Rich Orange Juice Intake and Altered Gut Microbiome in Young Adults with Depressive Symptom: A Randomized Controlled Study.
Nutrients (Nutrients ) Vol: 12 Issue: 6 Pages: Pub: 2020 Jun 18 ePub: 2020 Jun 18 Authors Park M,Choi J,Lee HJ
9 πŸ“šβ€ƒ
Alteration of Gut Microbiome and Correlated Lipid Metabolism in Post-Stroke Depression.
Frontiers in cellular and infection microbiology (Front Cell Infect Microbiol ) Vol: 11 Issue: Pages: 663967 Pub: 2021 ePub: 2021 Apr 22 Authors Jiang W,Gong L,Liu F,Ren Y,Mu J
10 πŸ“šβ€ƒ
Parabacteroides distasonis induces depressive-like behavior in a mouse model of Crohn`s disease.
Brain, behavior, and immunity (Brain Behav Immun ) Vol: Issue: Pages: Pub: 2021 Aug 14 ePub: 2021 Aug 14 Authors Gomez-Nguyen A,Basson AR,Dark-Fleury L,Hsu K,Osme A,Menghini P,Pizarro TT,Cominelli F
11 πŸ“šβ€ƒ
Association Between Non-Suicidal Self-Injury and Gut Microbial Characteristics in Chinese Adolescent.
Neuropsychiatric disease and treatment (Neuropsychiatr Dis Treat ) Vol: 18 Issue: Pages: 1315-1328 Pub: 2022 ePub: 2022 Jul 1 Authors Cai LF,Wang SB,Hou CL,Li ZB,Liao YJ,Jia FJ
12 πŸ“šβ€ƒ
Bacteroides species differentially modulate depression-like behavior via gut-brain metabolic signaling.
Brain, behavior, and immunity (Brain Behav Immun ) Vol: 102 Issue: Pages: 11-22 Pub: 2022 May ePub: 2022 Feb 7 Authors Zhang Y,Fan Q,Hou Y,Zhang X,Yin Z,Cai X,Wei W,Wang J,He D,Wang G,Yuan Y,Hao H,Zheng X
13 πŸ“šβ€ƒ
Changes of gut microbiota reflect the severity of major depressive disorder: a cross sectional study.
Translational psychiatry (Transl Psychiatry ) Vol: 13 Issue: 1 Pages: 137 Pub: 2023 Apr 28 ePub: 2023 Apr 28 Authors Hu X,Li Y,Wu J,Zhang H,Huang Y,Tan X,Wen L,Zhou X,Xie P,Olasunkanmi OI,Zhou J,Sun Z,Liu M,Zhang G,Yang J,Zheng P,Xie P
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Towards a psychobiotic therapy for depression: Bifidobacterium breve CCFM1025 reverses chronic stress-induced depressive symptoms and gut microbial abnormalities in mice.
Neurobiology of stress (Neurobiol Stress ) Vol: 12 Issue: Pages: 100216 Pub: 2020 May ePub: 2020 Mar 20 Authors Tian P,O'Riordan KJ,Lee YK,Wang G,Zhao J,Zhang H,Cryan JF,Chen W
89 πŸ“šβ€ƒ
Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: A randomized clinical trial.
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90 πŸ“šβ€ƒ
The outer membrane protein Amuc_1100 of Akkermansia muciniphila alleviates the depression-like behavior of depressed mice induced by chronic stress.
Biochemical and biophysical research communications (Biochem Biophys Res Commun ) Vol: 566 Issue: Pages: 170-176 Pub: 2021 Aug 20 ePub: 2021 Jun 12 Authors Cheng R,Xu W,Wang J,Tang Z,Zhang M
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The Role of Probiotics in Modulating Myocardial Infarction and Depression-like Symptoms: A Study on Sex-Specific Responses.
Biomedicines (Biomedicines ) Vol: 12 Issue: 11 Pages: Pub: 2024 Nov 2 ePub: 2024 Nov 2 Authors GagnΓ© MA,FrΓ©geau G,Godbout R,Rousseau G
92 πŸ“šβ€ƒ
The unique role of fluoxetine in alleviating depression and anxiety by regulating gut microbiota and the expression of vagus nerve-mediated serotonin and melanocortin-4 receptors.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (Biomed Pharmacother ) Vol: 182 Issue: Pages: 117748 Pub: 2025 Jan ePub: 2024 Dec 12 Authors Lee YB,Cho YJ,Kim JK
93 πŸ“šβ€ƒ
Lactobacillus rhamnosus: An emerging probiotic with therapeutic potential for depression.
Pharmacological research (Pharmacol Res ) Vol: 211 Issue: Pages: 107541 Pub: 2025 Jan ePub: 2024 Dec 7 Authors Feng J,Cen Q,Cui Y,Hu X,Li M,Wang L,Wei J,Sun N,Wang J,Zhang A
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Comparing the Effects of Selenium-Enriched Yeast and Sodium Selenite Supplementation on Postpartum Depression and Sexual Satisfaction: A Triple-Blind Controlled Clinical Trial.
Journal of caring sciences (J Caring Sci ) Vol: 13 Issue: 3 Pages: 197-206 Pub: 2024 Oct ePub: 2024 Sep 2 Authors Rahimi P,Farshbaf-Khalili A,Shahnazi M,Ostarahimi A,Mohammadi M
95 πŸ“šβ€ƒ
Effect of the arabinogalactan from Ixeris chinensis (Thunb.) Nakai. attenuates DSS-induced colitis and accompanying depression-like behavior.
International journal of biological macromolecules (Int J Biol Macromol ) Vol: 286 Issue: Pages: 138525 Pub: 2025 Jan ePub: 2024 Dec 6 Authors Gong X,Cai W,Yang D,Wang W,Che H,Li H
96 πŸ“šβ€ƒ
Promising Antidepressant Potential: The Role of Lactobacillus rhamnosus GG in Mental Health and Stress Response.
Probiotics and antimicrobial proteins (Probiotics Antimicrob Proteins ) Vol: Issue: Pages: Pub: 2025 Feb 17 ePub: 2025 Feb 17 Authors Isik M,KΓΆse F,Γ–zbayer C,Budak Γ–,Kaya RK,Erdogan DG,Demirci MA,Doganay S,Bagci C
97 πŸ“šβ€ƒ
Lactobacillus fermentum ATCC 9338 Supplementation Prevents Depressive-Like Behaviors Through Glucocorticoid Receptor and N-Methyl-D-aspartate2b in Chronic Unpredictable Mild Stress Mouse Model.
Molecular neurobiology (Mol Neurobiol ) Vol: Issue: Pages: Pub: 2025 Feb 17 ePub: 2025 Feb 17 Authors Tiwari S,Paramanik V
98 πŸ“šβ€ƒ
Bifidobacterium breve BB05 alleviates depressive symptoms in mice via the AKT/mTOR pathway.
Frontiers in nutrition (Front Nutr ) Vol: 12 Issue: Pages: 1529566 Pub: 2025 ePub: 2025 Jan 30 Authors Pan Y,Huang Q,Liang Y,Xie Y,Tan F,Long X
99 πŸ“šβ€ƒ
The effect of probiotic-fortified kefir on depression, appetite, oxidative stress, and inflammatory parameters in Iranian overweight and obese elderly: a randomized, double-blind, placebo-controlled clinical trial.
Journal of health, population, and nutrition (J Health Popul Nutr ) Vol: 44 Issue: 1 Pages: 30 Pub: 2025 Feb 7 ePub: 2025 Feb 7 Authors Noori M,Shateri Z,Babajafari S,Eskandari MH,Parastouei K,Ghasemi M,Afshari H,Samadi M
100 πŸ“šβ€ƒ
Jianghua Kucha black tea containing theacrine attenuates depression-like behavior in CUMS mice by regulating gut microbiota-brain neurochemicals and cytokines.
Food research international (Ottawa, Ont.) (Food Res Int ) Vol: 198 Issue: Pages: 115306 Pub: 2024 Dec ePub: 2024 Nov 3 Authors Jia W,Ma Q,Xing R,Yang X,Liu D,Zeng H,Liu Z,Liu S,Xu W,Liu Z,Wu W
101 πŸ“šβ€ƒ
The Impact of Akkermansia muciniphila on Mouse Models of Depression, Anxiety, and Stress: A Systematic Review and Meta-Analysis.
Current neuropharmacology (Curr Neuropharmacol ) Vol: Issue: Pages: Pub: 2025 Mar 18 ePub: 2025 Mar 18 Authors Khalili L,Park G,Nagpal R,Bhide P,Salazar G
102 πŸ“šβ€ƒ
Lactobacillus rhamnosus GG attenuates depression-like behaviour and cognitive deficits in chronic ethanol exposure mice by down-regulating systemic inflammatory factors.
Addiction biology (Addict Biol ) Vol: 29 Issue: 11 Pages: e13445 Pub: 2024 Nov ePub: Authors Pan X,Guo A,Guan K,Chen C,Xu S,Tang Y,Li X,Huang Z
103 πŸ“šβ€ƒ
Protective Effect of Exercise Against Depression, Anxiety, and Stress Among University Students Based on Their Level of Academic Performance.
Medicina (Kaunas, Lithuania) (Medicina (Kaunas) ) Vol: 60 Issue: 10 Pages: Pub: 2024 Oct 17 ePub: 2024 Oct 17 Authors Gosadi IM
104 πŸ“šβ€ƒ
Strain-specific effects of probiotics on depression and anxiety: a meta-analysis.
Gut pathogens (Gut Pathog ) Vol: 16 Issue: 1 Pages: 46 Pub: 2024 Sep 8 ePub: 2024 Sep 8 Authors Rahmannia M,Poudineh M,Mirzaei R,Aalipour MA,Shahidi Bonjar AH,Goudarzi M,Kheradmand A,Aslani HR,Sadeghian M,Nasiri MJ,Sechi LA
105 πŸ“šβ€ƒ
Probiotics and magnesium orotate for the treatment of major depressive disorder: a randomised double blind controlled trial.
Scientific reports (Sci Rep ) Vol: 14 Issue: 1 Pages: 20841 Pub: 2024 Sep 6 ePub: 2024 Sep 6 Authors Strodl E,Bambling M,Parnam S,Ritchie G,Cramb S,Vitetta L
106 πŸ“šβ€ƒ
Efficacy of Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Supplementation on Psychological Stress and Selective Fitness Profile Parameters in Female College Students in West Bengal, India.
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The Role and Mechanisms of Probiotic Supplementation on Depressive Symptoms: A Narrative Review.
Current nutrition reports (Curr Nutr Rep ) Vol: 14 Issue: 1 Pages: 53 Pub: 2025 Mar 28 ePub: 2025 Mar 28 Authors Dacaya P,Sarapis K,Moschonis G
108 πŸ“šβ€ƒ
The effects of Lactobacillus plantarum PS128 in patients with major depressive disorder: an eight-week double-blind, placebo-controlled study.
Asian journal of psychiatry (Asian J Psychiatr ) Vol: 101 Issue: Pages: 104210 Pub: 2024 Nov ePub: 2024 Aug 30 Authors Lin SK,Kuo PH,Hsu CY,Chiu YH,Chen CH
109 πŸ“šβ€ƒ
Bifidobacterium pseudonumeratum W112 alleviated depressive and liver injury symptoms induced by chronic unpredictable mild stress via gut-liver-brain axis.
Frontiers in nutrition (Front Nutr ) Vol: 11 Issue: Pages: 1421007 Pub: 2024 ePub: 2024 Aug 19 Authors Zhao J,Yuan J,Zhang Y,Deng L,Pan Y,Bai X,Jia L,Wang Y,Geng W
110 πŸ“šβ€ƒ
Faecalibacterium prausnitzii, FOS and GOS loaded synbiotic reverses treatment-resistant depression in rats: Restoration of gut-brain crosstalk.
European journal of pharmacology (Eur J Pharmacol ) Vol: 983 Issue: Pages: 176960 Pub: 2024 Nov 15 ePub: 2024 Aug 29 Authors Palepu MSK,Bhalerao HA,Sonti R,Dandekar MP
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An Analysis of the Intestinal Microbiome Combined with Metabolomics to Explore the Mechanism of How Jasmine Tea Improves Depression in CUMS-Treated Rats.
Foods (Basel, Switzerland) (Foods ) Vol: 13 Issue: 16 Pages: Pub: 2024 Aug 22 ePub: 2024 Aug 22 Authors Zhang Y,Lin Y,Xiong Y,Huang J,Liu Z
112 πŸ“šβ€ƒ
Antidepressant effect of carvedilol on streptozotocin-induced diabetic peripheral neuropathy mice by altering gut microbiota.
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113 πŸ“šβ€ƒ
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114 πŸ“šβ€ƒ
Bifidobacterium animalis subsp. Lactis A6 alleviates comorbid constipation and depression by rebalancing tryptophan metabolism.
Science bulletin (Sci Bull (Beijing) ) Vol: Issue: Pages: Pub: 2025 Apr 21 ePub: 2025 Apr 21 Authors Wang J,Ren Y,Chen J,Chen S,Li X,Chen J,Wang X,Li L,Zhao L,Li Y,Zhang Q,Xiong W,Guo H,Zhang H,Zhang X,Wang F,Hao Y,He J,Fang B,Guo J,Ge S,Ren F,Zhang L,Luo J,Wang R,Yin Y
115 πŸ“šβ€ƒ
Bacillus coagulans and Clostridium butyricum synergistically alleviate depression in a chronic unpredictable mild stress mouse model through altering gut microbiota and prefrontal cortex gene expression.
Frontiers in pharmacology (Front Pharmacol ) Vol: 15 Issue: Pages: 1393874 Pub: 2024 ePub: 2024 May 23 Authors Xu J,Zhou L,Chen Z,Wang Y,Xu F,Kuang Q,Zhang Y,Zheng H
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Chronic exercise effects on overall depression severity and distinct depressive symptoms in older adults: A protocol of a systematic and meta-analytic review.
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117 πŸ“šβ€ƒ
Mental Health and Health-related Quality of Life Response to Curcumin-Probiotic Drink Powder Co-supplementation in Adults with Overweight/Obesity and Metabolic Syndrome: a Four-arm Randomized, Double-blind, Placebo-controlled, Clinical Trial.
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119 πŸ“šβ€ƒ
Exercise mitigates a gut microbiota-mediated reduction in adult hippocampal neurogenesis and associated behaviours in rats.
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120 πŸ“šβ€ƒ
Associations between regular physical exercise and physical, emotional, and cognitive health of older adults in China: an 8-year longitudinal study with propensity score matching.
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Akkermansia muciniphila reverses neuronal atrophy in Negr1 knockout mice with depression-like phenotypes.
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122 πŸ“šβ€ƒ
Abnormal Weight Gain and Gut Microbiota Modifications Are Side Effects of Long-Term Doxycycline and Hydroxychloroquine Treatment
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GUT MICROBIOTA DYSBIOSIS IS LINKED TO HYPERTENSION
Hypertension (Hypertension ) Vol: 65 Issue: 6 Pages: 1331-1340 Pub: 2015 Apr 13 ePub: 2015 Apr 13 Authors Yang T,Santisteban MM,Rodriguez V,Li E,Ahmari N,Carvajal JM,Zadeh M,Gong M,Qi Y,Zubcevic J,Sahay B,Pepine CJ,Raizada MK,Mohamadzadeh M
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Modulation of the gut microbiota composition by rifaximin in non-constipated irritable bowel syndrome patients: a molecular approach
Clinical and Experimental Gastroenterology (Clin Exp Gastroenterol ) Vol: 8 Issue: Pages: 309-325 Pub: 2015 Dec 4 ePub: 2015 Dec 4 Authors Soldi S,Vasileiadis S,Uggeri F,Campanale M,Morelli L,Fogli MV,Calanni F,Grimaldi M,Gasbarrini A
125 πŸ“šβ€ƒ
The Influence of Nonsteroidal Anti-Inflammatory Drugs on the Gut Microbiome
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases (Clin Microbiol Infect ) Vol: 22 Issue: 2 Pages: 178.e1-178.e9 Pub: 2015 Oct 16 ePub: 2015 Oct 16 Authors Rogers MA,Aronoff DM
126 πŸ“šβ€ƒ
Impact of probiotic supplements on microbiome diversity following antibiotic treatment of mice
Gut Microbes (Gut Microbes ) Vol: 7 Issue: 2 Pages: 101-114 Pub: 2016 Mar 10 ePub: 2016 Mar 10 Authors Grazul H,Kanda LL,Gondek D
127 πŸ“šβ€ƒ
Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men
The ISME Journal (ISME J ) Vol: 8 Issue: 11 Pages: 2218-2230 Pub: 2014 Apr 24 ePub: 2014 Apr 24 Authors Salonen A,Lahti L,SalojΓ€rvi J,Holtrop G,Korpela K,Duncan SH,Date P,Farquharson F,Johnstone AM,Lobley GE,Louis P,Flint HJ,de Vos WM
128 πŸ“šβ€ƒ
Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier
World Journal of Gastroenterology (World J Gastroenterol ) Vol: 23 Issue: 1 Pages: 60-75 Pub: 2017 Jan 7 ePub: 2017 Jan 7 Authors Zhou D,Pan Q,Xin FZ,Zhang RN,He CX,Chen GY,Liu C,Chen YW,Fan JG
129 πŸ“šβ€ƒ
Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior
Nature Communications (Nat Commun ) Vol: 8 Issue: Pages: 15062 Pub: 2017 Apr 4 ePub: 2017 Apr 4 Authors Leclercq S,Mian FM,Stanisz AM,Bindels LB,Cambier E,Ben-Amram H,Koren O,Forsythe P,Bienenstock J
130 πŸ“šβ€ƒ
Energy-dense diet triggers changes in gut microbiota, reorganization of gut-brain vagal communication and increases body fat accumulation
Acta neurobiologiae experimentalis (Acta Neurobiol Exp (Wars) ) Vol: 77 Issue: 1 Pages: 18-30 Pub: 2017 ePub: Authors Vaughn AC,Cooper EM,DiLorenzo PM,O’Loughlin LJ,Konkel ME,Peters JH,Hajnal A,Sen T,Lee SH,de La Serre CB,Czaja K
131 πŸ“šβ€ƒ
Effects of One-Week Empirical Antibiotic Therapy on the Early Development of Gut Microbiota and Metabolites in Preterm Infants
Scientific Reports (Sci Rep ) Vol: 7 Issue: Pages: 8025 Pub: 2017 Aug 14 ePub: 2017 Aug 14 Authors Zhu D,Xiao S,Yu J,Ai Q,He Y,Cheng C,Zhang Y,Pan Y

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